In theory, could all mammals be wiped out by a single pathogen?

Pathogen

Note: For the purpose of this question I define a pathogen to include viruses and/or bacteria. Edit: I don't exclude other biological agents such as fungi that might have the same effect.

Pathogen

A pathogen or infectious agent is a biological agent that causes disease or illness to its host.

https://www.sciencedaily.com/terms/pathogen.htm

Sometimes we hear of a potential threat to humanity from a 'killer' virus, for example bird-flu. https://www.webmd.com/cold-and-flu/flu-guide/what-know-about-bird-flu#1

There have been plagues that have killed vast numbers of people but none have resulted in actual extinction. https://www.mphonline.org/worst-pandemics-in-history/

HIV Aids, Bird-Flu and others have affected more than one species.

Question

In theory could a microbe arise that could completely wipe out an entire species (in particular humans) or more importantly all mammals (and maybe other species as well).

Clearly mammals have not all been wiped out so far because we are still around. My question is, could it conceivably happen given what we currently know? If not, what would prevent it?

Edit I should repeat that I want it to be an agent that directly infects mammals by getting into their bloodstream or other bodily systems - not one that affects them indirectly.

posted over 5 years ago

chasly from UK‭

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