Biological Coolant System for Massive Organisms

The larger an animal, the harder it is to cool down. Ignoring the problem of bone/muscle strength vs size/weight and saying an animal could get to outlandish sizes, would a second cardiovascular system specifically for thermoregulation help it regulate its core body temperature? What would the fluid in question be, assuming this hypothetical organism is of terran biochemistry?

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Biological Coolant System for Massive Organisms

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