Does a life form not using a food-based metabolism still need to saturate its cells with respiratory gases?

I've quite a few alien species that utilize a non-food-based metabolism (one of them being nuclear power).

Does a species that has a metabolism not based-on plants or meat (such as using nuclear power, solar power, natural gas, etc., instead) still need respiratory gases to saturate their cells? If not, what type of system would and/or should they have?

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Does a life form not using a food-based metabolism still need to saturate its cells with respiratory gases?

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