What would happen if Aromatase turned much of a man`s testosterone levels into estrogen?

I'd like to create a story in which a genetically modified man has Aromatase Excess syndrome.

For example, if a man has a genetic mutation where he produces a lot of aromatase that turns 10% of his testosterone levels into estrogen (specially estradiol), what would happen to his body?

Consider that the fictitious man in this case has a testosterone level of 500 ng/dl or 5ng/ml and aromatase is turning 10% of his testosterone into estrogens. A healthy level of estrogen in a young woman is between 80-200 pg/ml of blood, then 10% of 500000pg (500ng) is 50000 picograms or 50nanograms of estrogen.

What would happen if a man had 50000 pg of estradiol, which is many times higher than the average level of estrogen in a woman?

posted almost 5 years ago

Sabrine Crystal Santos‭

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