Could genetic engineering enable humans to make use of titanium or some similar material instead of calcium for bone formation?

I'm planing to create "super powers" born out of genetic engineering, but I don't want magic miracle stuff like an x-man, I'm looking for a realistic approach, so overall can you modify the materials biology uses to create us?

Edit: as suggested I'm adding abundance, bio availability and usefulness requirements to the mix of materials that could be used, feel free to add any material that is plausible.

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Could genetic engineering enable humans to make use of titanium or some similar material instead of calcium for bone formation?

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