Is there a hypothetical scenario that would make Earth uninhabitable for humans, but not for (the majority of) other animals?

I'm trying to think of a scientifically plausible reason for humanity to be forced to abandon earth that would leave animals and plants largely untouched. Is there any natural disaster that would have such an effect? If not, is it possible for humanity to develop a weapon that would unintentionally have this effect?

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Is there a hypothetical scenario that would make Earth uninhabitable for humans, but not for (the majority of) other animals?

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