Can you create a living vehicle fueled by organic material?

In this world, the vehicles are effectively re-engineered insects; enlarged bio-manufactured nervous systems used instead of engines; factory grown lightweight chassis / [wheels]. The fuel station could be an algae pit or something similar.

My question is basically, if you could redesign an insect's shape and size to be similar to that of a small 4x4, how much fuel would it require to get say 200miles? what kind of oxygen intake it would it need to function? and, as a bonus question, what kind of technology (or biotech) could be used to command the vehicle?

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Can you create a living vehicle fueled by organic material?

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