Flipped over through fourth dimension. When do I start to notice biological problems?

In the middle of the night, while J. Random Human is sleeping, A. Hypersphere picks him hyper-up extremely carefully (so that none of his matter falls out in a direction he doesn't have), flips him over through a fourth spatial dimension, and puts him back hyper-down in his bed. When he wakes up, the entire world is mirror-imaged to him. Everybody looks slightly weird, finding his way around becomes very difficult, reading is an ordeal.

What biological differences does J. Random notice, and how quickly does he notice them? I know the chirality of biological molecules is going to be an issue (and will probably eventually kill him), but do the foods he eats smell and taste different? What symptoms does he start experiencing?

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Flipped over through fourth dimension. When do I start to notice biological problems?

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