How would industrial civilizations contacting each other for the first time protect themselves from diseases?

In a world big enough for human civilizations as knowledgeable about medicine as ours to develop without contacting each other, how could they initiate that contact without exposing each other to potentially deadly diseases?

For example, say a contact team from civilization A reaches the borders of a new civilization, B. If I have my facts straight, they could potentially inoculate themselves using the blood of a volunteer from B, but could there be a way for them to interact with regular society without all of Civilisation B getting shots?

Or am I overestimating the danger of this, and the likelihood of the contact team from A being asymptomatic carriers of some disease deadly to B is actually very small?

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How would industrial civilizations contacting each other for the first time protect themselves from diseases?

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