Could a human with a regenerative factor use (and get addicted to) drugs such as alcohol, narcotics, stimulants, etc.?

I'm working on a sci fi story with bio-punk elements in it (such as gene manipulation). This has brought up a problem with one of the sub plots, however, as I am unaware of whether or not an extreme healing factor would make the effects of certain drugs null and void. The main character has a healing factor that can heal him from everything except specialized venoms and EXTREME bodily harm. He acquired this healing factor by a combination of nanobots and a genetic alteration in the form of a injection that simply added genes to him (specifically the regenerative genes of the axolotl). Any help would be greatly appreciated.

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Could a human with a regenerative factor use (and get addicted to) drugs such as alcohol, narcotics, stimulants, etc.?

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