What conditions may lead to an intelligent civilization employing only bio-machines?
Suppose a civilization in which every possible appliance is a bio-machine. There are automobiles, but each one has a human-like head under the hood. Each datacenter is a bunch of over-grown brains. There are artificial udders that produce milk without a cow. Each house is living as well. When you sit in a chair it embraces you with its hands etc.
Everything is based on mutated animal and/or human genomes, but the civilization evolved from human society.
There are no steel/plastic machines, there is no use of mains electricity. There is no internet (but neural networks are possible).
What conditions may lead a human civilization to pursue advances in bio-engineering but reject other technologies?
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