Realistic limits to the transforming abilities of nanomachines?

We all know how fiction likes to play fast and loose with nanomachines. But really, what would they be capable of in real life, assuming you had an utterly arbitrary amount of them? What would the timescale be? Would you ever be able to shapeshift or use nanomachine-based superpowers, or is that all strictly fantasy no matter what limitations you put on it?

Basically, what separates the IRL potential of nanotechnology in the near future from "NANOMACHINES, SON"?

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Realistic limits to the transforming abilities of nanomachines?

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