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Rare and long-lived humans

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I would like some rare humans (1 in 10 million) to have a mutation that increases their lifetime by a factor of three. In other words, these rare humans could live for ~240 years on average.

But I also need to have one of these constraints:

  1. This mutation is not transferable to their children; or
  2. This mutation is transferable to their children, but on a 1/100 ratio, i.e., only 1 out of 100 children has the same mutation; or
  3. They could transfer their mutation, but they are almost sterile (rare chances of having one child during their lifetime).

Which one of these alternatives is more realistic, from a biologic point of view?

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This post was sourced from https://worldbuilding.stackexchange.com/q/29744. It is licensed under CC BY-SA 3.0.

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