What natural or human-induced disaster could bring to a scenario like in McCarthy's "The Road'?

This post-apocalyptic environment, as narrated in the book, depicts a world where most if not all animal life has been abruptly killed, and similarly most vegetation burned out. After the disaster, the world is left full of ash and fog, and turned cold.

What kind of disaster can cause such an environment? I could think of some possible causes, like eruptions, or maybe a space object collision, or even nuclear warfare, but I'd like to get some scientific-based reasoning.

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What natural or human-induced disaster could bring to a scenario like in McCarthy's "The Road'?

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