Are infections necessary for human colonisation?

If a human colony is set up on another planet or moon, or in an orbiting habitat, most of the infectious diseases from Earth would not be present in the small initial population. Careful screening could further reduce the number of infectious diseases introduced. Would the human immune system suffer problems if infection is reduced too much? Would we need to take some token infections (such as the cold) with us?

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Are infections necessary for human colonisation?

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