What is the highest acceleration that a normal human could safely endure for (say) 8 hours?

Assuming constant acceleration to midpoint and constant deceleration after that, what's the highest g-force I could sensibly inflict on my passengers without breaking them?

I'm assuming that they're seated (or lying oriented in the most sensible way, etc) and strapped in throughout the journey.

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What is the highest acceleration that a normal human could safely endure for (say) 8 hours?

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